A nurse asked our pharmacist if she could hang potassium chloride with tpn ysite the potassium to the tpn. Compatibility depends upon many factors including temperature, ph, iv fluid, concentration, order of mixing and brand of drug. Acetaminophen retained greater than 99% of its original concentration throughout. The patient has a 22gauge peripheral iv in his right forearm and reports pain at the insertion site. Zosyn is not chemically stable in solutions that contain only sodium bicarbonate and solutions that significantly alter the ph. Hyperkalemia excess potassium is the most serious adverse effect of potassium intake and occurs when the intake exceeds excretion leading to elevated serum potassium concentrations. The normal potassium ion content of human milk is about meql. Administer by slow iv infusion y injection port of minibore tubing. Monographs for commonly administered intravenous medications. If storage is necessary, hold at 28c for not more than 24 hours.
Although data are limited, potassium supplements appear to be safe and effective to use during breastfeeding to help meet maternal nutritional requirements. In the 1980s and 1990s, the institute for safe medication practices ismp, the u. It is a sterile, preservativefree solution of potassium chloride bp in water for injections bp. Gynecologic and obstetric infections postpartum endometritis or pid iv 3. Potassium chloride injection potassium chloride dose. Find patient medical information for potassium acetate intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pharmacopeia usp, the joint commission, and the institute for healthcare improvement ihi drew much needed attention to the removal of concentrated potassium chloride kcl vials from patientcare areas. Potassium chloride injection has been reported to be compatible with the following iv infusion fluids. This study is created by ehealthme based on reports of 50 people who take potassium chloride and zosyn from food and drug administration fda, and is. Potentially fatal hyperkalaemia can develop rapidly and be asymptomatic. Product information sterile potassium chloride concentrate potassium chloride name of the medicine the australian approved name is potassium chloride. Best practice guidelines for the safe use of intravenous.
Zosyn is a combination product consisting of a penicillinclass antibacterial, piperacillin, and a. This protocol has been developed based upon the need for providing safe and effective guidelines for the infusion of intravenous potassium salts and to reduce the occurrence or potential occurrence of medication errors or adverse effects. Iv potassium may be required in patients with marked hypokalemia. Intraabdominal infections appendicitis andor peritonitis iv. You should also ensure that the drugs checked are compatible in terms of carrier fluid. Physical compatibility for microscopic disc measurements at hour 4 indicated that the crystalline particulate count exceeded the usp recommendations for acyclovir and diazepam table 1. Intravenous iv preparation and infusion guidelines globalrph. Many elderly and frail patients requiring parenteral potassium supplementation are readily at risk of volume overload if administered potassium salts in. Response to intravenous potassium chloride supplementation in.
Keep iv fluids running to ensure further dilution of potassium. All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. Normal saline is the only compatible solution to use with blood or blood components. Fatal or serious incidents related to iv potassium.
With blood transfusions, the iv line is primed with 0. Parenteral nutrition pn and drug compatibility only if a. I am starting to feel some is there a better h bp medicine other than lisonopril and losartan that also does not contain diuretics or potassium. Editor, recommendations from the safety and quality council regarding the highrisk medication alert. See what the interactions are and for which people. This is of particular concern in patients given iv potassium. Medication distribution intravenous potassium administration n 1107a intent.
Boluses of potassium may cause severe and potentially fatal rhythm disturbances, so careful monitoring is required. Iv ysite infusion solution compatibility data infusion solution compatible. Visual compatibility of azithromycin with 24 commonly used. It is also used as an additive in the preparation of fluid formula injections. The molecular formula is kcl and the cas number is 7447407.
Intravenous admixtures preparation and infusion guidelines. Each monograph contains stability data, administration guidelines, and methods of preparation. Learn about drug interactions between piperacillintazobactam iv and tobramycindexamethasone opht and use the rxlist drug interaction checker to check drug combinations. The study is based on potassium chloride and piperacillin sodium. This can occur with acute or chronic renal failure, hypoaldosteronism, the use of potassium sparing diuretics, ace inhibitors, or other drugs, and also with. Potassium phosphate injection is a phosphate supplement that is used to treat or prevent hypophosphatemia low phosphorus in the blood. Aug 22, 2019 potassium chloride in 5% dextrose injection usp is sterile, nonpyrogenic and contains no bacteriostatic or antimicrobial agents. Monographs for commonly administered intravenous medications in home and community care references. It is a list of 33 antibiotics and their given stability in several different solutions.
Eight of the medications were further tested to assess chemical compatibility. Sterile potassium chloride concentrate is a sterile solution of potassium chloride in water for injections, containing no preservatives. Pr piperacillin sodiumtazobactam sodium powder for injection. Trissel, fashp, 2010, american society of healthsystem pharmacists. Other drugs that have the same active ingredients e. Pharmacology potassium ion is the principal intracellular ion of most body tissues. Visual compatibility of azithromycin with 24 commonly used drugs. Zosyn should not be added to blood products or albumin hydrolysates. This reference contains standard dilutions including iv admixture drug concentration, infusion volumes, and infusion rates. Antibiotic compatibility chart wes cains health science.
Intravenous compatibility chart free html5 flip book. Oct 11, 2018 oral potassium preparations include 8 meq kci slowrelease tablets, 20 meq kci elixir, 20 meq kci powder, 25 meq kci tablet. This protocol has been developed based upon the need for providing safe and effective guidelines for the infusion of intravenous potassium salts and to reduce the occurrence. Drug interactions are reported among people who take potassium chloride and zosyn together. Management of potassium administration auckland city hospital. The antibiotics are listed on the yaxis and along the xaxis are the most commonly used iv solutions. Do not mix with other drugs, blood or blood products.
Pn solutions are diverse in their composition and compatibilities with drugs can never be guaranteed. Care should be exercised if potassium salts are given concomitantly with potassiumsparing diuretics, as hyperkalaemia may result see section 4. All patients receiving iv diuretics who had a serum potassium level less than 4. Crystalloid solutions and medications may cause agglutination and. Potassium chloride injection has been reported to be compatible with the. Zosyn piperacillin, tazobactam dosage and administration. Thames valley ysite intravenous drugs compatibility chart march. Use potassium gluconate during pregnancy only if the potential benefit justifies the potential risk to the fetus. Parenteral nutrition pn and drug compatibility the coinfusion of drugs and pn should be avoided. This table was compiled for the convenience of the pharmacists tending to calls about iv compatibility. Potassium chloride and zosyn drug interactions a study of. Iv drug compatibility chart the iv drug compatibility chart is based on information from the handbook of injectable drugs, 16th edition, by lawrence a.
Intravenous potassium chloride australian prescriber. Concentrated sodium chloride and potassium chloride will be stocked in one concentration and all compounding templates will utilize the standard concentration. Always specify the potassium preparation phosphate or chloride to be used. Parenteral must be diluted prior to administration. The pharmacist told her that it was okay because there were no compatibility issues, but some of my coworkers and i told her not to do it.
Response to intravenous potassium chloride supplementation. Check tubing below ysite carefully for discoloration, cloudiness or precipitation blank do not mix. Potassium chloride injection still poses threats to patients. Maintain close followup care, provide continuous ecg monitoring, and check serial potassium levels. Zosyn should not be mixed with other drugs in a syringe or infusion bottle since compatibility has not been established. In the symptomatic patient with severe hypokalemia, administer up to 40 meqh of the iv preparation. Potassium chloride and dextrose fda prescribing information. Potassium phosphate intravenous route description and brand.
A 2002 joint commission national patient safety goal sustained this effort, and virtually all u. You can publish your book online for free in a few minutes. Potassium ions are involved in a number of essential physiological processes, including the. Jan 08, 2014 visual clarity was maintained in all aliquots at 0 and 4 hours, except for diazepam. Administration of iv potassium chloride is a potentially dangerous procedure, where errors in calculation, preparation of potassium containing iv solutions or too rapid rate of administration can result in death. Oral potassium can be prescribed in conjunction with iv potassium. Compatible for coinfusion with ivn at y injection site. Unasyn compatibility with potassium unasyn 3 gm iv is unasyn a sulfa drug unasyn for vre usages of unasyn download here free healthcaremagic app to ask a doctor. Infiltration of potassium saltcontaining solutions can cause severe chemical burns and skin sloughing. Potassium is an essential mineral which is an important electrolyte in the body along with sodium and chloride. Intravenous compatibility chart drug information for the. If patient specific factors require that a nonstandard concentration be used, the drug will be separated in. Potassium chloride in 5% dextrose injection usp is sterile, nonpyrogenic and contains no bacteriostatic or antimicrobial agents.
Safe prescribing of intravenous potassium and other. Dose and rate of administration are dependent on patient condition. Ysite injection drug compatibility chart for general wards. Careful monitoring of serum potassium levels during administration and appropriate adjustment of dosage is essential.
The top five highalert medications identified by the ismp are i insulin, ii opiates and narcotics, iii injectable potassium chloride or phosphate concentrate 2, iv intravenous. Indications, dose, contraindications, sideeffects, interactions, cautions, warnings and other safety information for potassium chloride. Compatibility depends upon many factors including temperature, ph, iv fluid, concentration, order of mixing and brand of. Potassium chloride drug bnf content published by nice. For children with appendicitis and or peritonitis 9 months of age or older, weighing up to 40 kg, and with normal renal function, the recommended zosyn dosage is 100 mg piperacillin12. We would like to show you a description here but the site wont allow us. Ysite injection drug compatibility chart for general. Readymixed infusion solutions should be used where possible.
Unasyn compatibility with potassium doctor answers on. Cached iv medication solution compatibility chart for nurses free download as pdf file. For additional information or clarification, call pharmacy. Medication distribution intravenous potassium administration. The potential benefit of iodine prophylaxis is greatest in the young.
Individualize dose based on serum potassium levels. A patient is receiving 10 meq of potassium chloride in 100 ml of normal saline intravenously to infuse over 1 hours via infusion pump. Potassium salts should be given cautiously to patients with renal or adrenal insufficiency, acute dehydration or heat cramp. Sterile potassium chloride concentrate product information. Incompatibilities are based on meeting any of the following criteria. The australian council for safety and quality in health care has issued a highrisk medication alert for intravenous potassium chloride see box for recommendations. Pdf pharmacists interventions on intravenous to oral. Not compatible with bicarbonate, calcium, phosphate salts. Potassium phosphate intravenous route description and.1497 252 153 299 262 1142 509 103 1280 1350 216 757 95 710 1435 1429 349 442 1386 258 44 385 1069 717 259 362 1217 65 886 1474 351 836 841 466 1232 285 97 1441 203